Null Responders:   Poor Bastards and Horse Racing

Being a null responders is kinda like paying for your horse to run in the Kentucky Derby, going to the first turn, watching all the other horses go by and realizing that your horse never left the gate.  You put all your money and resources on that horse and ….he is a fizzle.  This is one opportunity I missed!  When you enter a treatment or a study, that is the horse you pick.  Put some research into picking your horse. At the end of the day, everyone else tears up their ticket.  You gotta load up that horse and take it home.

Note on the graph below by Vertex is an example of full, partial, breakthrough and null responder

http://www.vrtx.com/assets/pdfs/VRTXHCVTreatmentResponse.pdf